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Related Concept Videos

Larynx01:21

Larynx

The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids, corniculates, and...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.

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Related Experiment Video

Updated: May 29, 2026

Construction and Characterization of a Novel Vocal Fold Bioreactor
11:11

Construction and Characterization of a Novel Vocal Fold Bioreactor

Published on: August 1, 2014

Vocal fold cancer.

P Schultz1

  • 1Service d'ORL et de chirurgie cervicofaciale, hôpital de Hautepierre, hôpitaux universitaires de Strasbourg, avenue Molière, 67098 Strasbourg cedex, France. philippe.schultz@chru-strasbourg.fr

European Annals of Otorhinolaryngology, Head and Neck Diseases
|October 1, 2011
PubMed
Summary
This summary is machine-generated.

Vocal fold squamous cell carcinoma, primarily linked to smoking, shows decreasing male and increasing female incidence. Early detection via dysphonia is key for effective treatment and improved survival rates.

More Related Videos

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp
09:58

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp

Published on: February 3, 2014

Related Experiment Videos

Last Updated: May 29, 2026

Construction and Characterization of a Novel Vocal Fold Bioreactor
11:11

Construction and Characterization of a Novel Vocal Fold Bioreactor

Published on: August 1, 2014

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp
09:58

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp

Published on: February 3, 2014

Area of Science:

  • Otolaryngology
  • Oncology
  • Head and Neck Surgery

Background:

  • Vocal fold squamous cell carcinoma constitutes 90% of vocal fold cancers.
  • Incidence trends show a decline in males and a rise in females since the 1980s in France.
  • Smoking is the primary risk factor, with alcohol playing a lesser role compared to other head and neck cancers.

Purpose of the Study:

  • To review the epidemiology, risk factors, and clinical presentation of vocal fold squamous cell carcinoma.
  • To discuss diagnostic and pretreatment assessment strategies.
  • To outline treatment options and outcomes for vocal fold squamous cell carcinoma.

Main Methods:

  • Literature review of vocal fold squamous cell carcinoma.
  • Analysis of epidemiological data and risk factors.
  • Summary of diagnostic modalities and treatment approaches.

Main Results:

  • Dysphonia is the initial symptom, progressing from mucosal vibration defects to vocal fold fixation.
  • Transoral resection requires precise determination of tumor limits.
  • High 5-year local control rates are reported for T1 (85-95%) and T2 (60-90%) tumors with surgery or radiation therapy.

Conclusions:

  • Vocal fold squamous cell carcinoma management requires individualized treatment plans.
  • Smoking cessation, surveillance, and cardiovascular prevention are crucial post-treatment.
  • Multidisciplinary care is essential for optimal patient outcomes and screening for secondary malignancies.