Related Experiment Video
Updated: May 29, 2026

06:26
Quantitative Assessment Protocol for Facial Soft Tissue Volumetric Changes with Stereophotogrammetry
Published on: December 9, 2025
Measuring progressive soft tissue change with nasoalveolar molding using a three-dimensional system.
Erika Simanca1, David Morris, Linping Zhao
1Division of Plastic Surgery, The Craniofacial Center (MC 588), 811 S Paulina St, Chicago, IL 60612, USA. esiman2@uic.edu
The Journal of Craniofacial Surgery
|October 1, 2011
Summary
Accurate 3D imaging of infants with cleft lip and palate shows progressive nasal changes during presurgical nasoalveolar molding. Measurements reveal significant alterations by week 4, aiding craniofacial treatment planning.
Area of Science:
- Craniofacial orthodontics and surgery
- Pediatric plastic surgery
- 3D imaging and analysis
Background:
- Accurate temporal evaluation of soft tissue and skeletal changes is crucial for advancing craniofacial orthodontics and surgery.
- Three-dimensional (3D) imaging offers solutions to challenges in measuring changes in infants with facial clefts.
- Presurgical nasoalveolar molding (PNAM) is a common treatment for infants with cleft lip and palate.
Purpose of the Study:
- To measure progressive 3D changes in nasal form in infants with facial clefts during PNAM.
- To evaluate the efficacy of 3D photography for monitoring nasal changes during PNAM.
- To provide quantitative and qualitative data on nasal soft tissue development in response to PNAM.
Main Methods:
- Utilized the 3dMD 3D photographic system to capture serial images of 5 infants with unrepaired cleft lip and palate.
- Acquired 3D photographs at 2-week intervals throughout the PNAM treatment period.
- Employed 3dMD Vultus software for quantitative analysis of linear nasal landmarks and qualitative assessment of surface shell changes.
Main Results:
- Observed consistent increases in columellar length on the cleft side across all subjects.
- Noted a decrease in nostril floor on the noncleft side in all infants studied.
- Identified the most significant progressive nasal changes occurring by week 4 of PNAM treatment.
Conclusions:
- The 3dMD 3D photo system combined with Vultus software provides a valuable method for quantifying progressive nasal soft tissue changes in infants undergoing PNAM.
- This approach offers a reliable tool for facial analysis in the context of cleft lip and palate treatment.
- The findings support the use of advanced 3D imaging for monitoring treatment outcomes in pediatric craniofacial patients.

