Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...

Acute Coronary Syndrome III: Diagnostic Studies

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...

Myocarditis I: Introduction

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...

Angina II: Classification

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Nationwide survey reveals gender disparities in cardiovascular awareness and lifestyle behaviors among polish adolescents aged 18 years.

Scientific reports·2026

Same author

Proteostasis, disease and the ageing neuron: Compartmental complexity in non-renewing cells.

Ageing research reviews·2026

Same author

Cardiac intensive care units in Poland: A report of the expert panel for the systemic evaluation of the functioning of cardiac intensive care units in Poland.

Kardiologia polska·2026

Same author

In-hospital and 1-year outcomes of mitral transcatheter edge-to-edge repair in Poland derived from an all-comers administrative database.

Kardiologia polska·2026

Same author

Successful invasive treatment of stroke in a patient with a left ventricle assist device - case report.

Postepy psychiatrii neurologii·2026

Same author

Colocalizing Telomeres With PML or γH2AX Foci by IF-FISH in Mouse Brain Neurons.

Bio-protocol·2025

Search research articles

Related Experiment Video

Updated: May 29, 2026

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

A severe complication after ST-segment elevation myocardial infarction (Part 2).

Anna Konopka¹, Małgorzata Stępień-Wojno, Miłosz Marona

¹Intensive Cardiac Therapy Clinic, Institute of Cardiology, Warsaw, Poland. akonopka@ikard.pl

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

|October 1, 2011

Summary

A 70-year-old woman with ST-segment elevation myocardial infarction experienced ventricular septal rupture and cardiogenic shock. Surgical repair of the ventricular septal defects (VSDs) led to a good clinical outcome after conservative management.

More Related Videos

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Published on: May 28, 2019

Myocardial Infarction and Functional Outcome Assessment in Pigs

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

Related Experiment Videos

Last Updated: May 29, 2026

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Published on: May 28, 2019

Myocardial Infarction and Functional Outcome Assessment in Pigs

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

Area of Science:

Cardiology
Cardiac Surgery

Background:

ST-segment elevation myocardial infarction (STEMI) can lead to serious mechanical complications.
Ventricular septal rupture (VSD) is a rare but life-threatening complication following myocardial infarction.

Observation:

A 70-year-old female patient presented with anterior STEMI complicated by cardiogenic shock.
Two ventricular septal defects (VSDs) were identified as the cause of the cardiogenic shock.

Findings:

Initial conservative management included inotropes and intra-aortic balloon pump support for 6 weeks.
Surgical repair of the VSDs was successfully performed.
The patient achieved a good clinical outcome post-surgery.

Implications:

Early identification and management of VSD are crucial in STEMI patients.
Surgical VSD repair can be effective in improving outcomes for patients with cardiogenic shock post-MI.
This case highlights the potential for successful surgical intervention in complex post-MI mechanical complications.