Related Experiment Video
Updated: May 29, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Late angiograms ten years after transmyocardial laser revascularization
Fabrizio Sansone1, Guglielmo Mario Actis Dato, Edoardo Zingarelli
1Division of Cardiac Surgery, Mauriziano Umberto I Hospital, Turin, Italy. fabrisans@katamail.com
Abstract:
We present the angiograms of a patient after transmyocardial laser revascularization (TMR), which were performed 10 years before by the application of holmium laser pulses. Thirteen years before the TMR procedure, the patient underwent coronary artery bypass graftings complicated by graft occlusion with no longer possibility of direct revascularization. Then, refractive angina required an alternative approach for symptom relief as the indirect revascularization by the application of the holmium laser pulses. Interestingly, the late angiograms, taken when the patient suffered from effort dyspnea for ongoing left ventricular dysfunction, showed a network of small vessels (absent before the TMR procedure) that supplies blood to the heart with no flow through the coronary arteries because of their complete occlusion. This is a historical presentation of the results of TMR to understand the effects of the indirect revascularization on the blood circulation through the heart over the long-term follow-up.
More Related Videos
09:12Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
09:37Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
Published on: December 2, 2014