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Histamine receptor assays
N P Shankley1, M F Morton, G F Watt
1R.W. Johnson Pharmaceutical Research Institute, La Jolla, California, USA.
Current Protocols in Pharmacology
|October 1, 2011
Abstract:
This unit describes three standard in vitro bioassays for studying histamine H₁, H₂ and H₃ receptors in isolated intact tissues removed from the guinea pig. Both the H₁ and H₃ receptor assays are based on preparations of the ileum, whereas the spontaneously beating right atrium assay is used for the H₂-receptor.This unit describes three standard in vitro bioassays for studying histamine H₁, H₂ and H₃ receptors in isolated intact tissue.
