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Updated: May 28, 2026

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks (MOFs)
Published on: January 17, 2020
Application of a chiral metal-organic framework in enantioselective separation
Mohan Padmanaban1, Philipp Müller, Christian Lieder
1Westfälische Wilhelms-Universität, NRW Graduate School of Chemistry, Organisch-Chemisches Institut, Corrensstr. 40, 48149 Münster, Germany.
Abstract:
A modular approach for the synthesis of highly ordered porous and chiral auxiliary (Evans auxiliary) decorated metal-organic frameworks is developed. Our synthesis strategy, which uses known porous structures as model materials for incorporation of chirality via linker modification, can provide access to a wide range of porous materials suitable for enantioselective separation and catalysis. Chiral analogues of UMCM-1 have been synthesized and investigated for the enantioseparation of chiral compounds in the liquid phase and first promising results are reported.
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