Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prediction of salt sensitivity.

J E Dimsdale1, M Ziegler, P Mills

  • 1Department of Psychiatry, University of California, San Diego, La Jolla 92093.

American Journal of Hypertension
|June 1, 1990
PubMed
Summary

High salt intake decreased diastolic blood pressure in all men but increased systolic pressure in some hypertensives, particularly Black individuals. This suggests personalized salt recommendations for hypertension management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Traditional left ventricular indices outperform novel cardiovascular magnetic resonance-derived left atrial parameters in predicting adverse left ventricular remodelling after ST-segment elevation myocardial infarction.

International journal of cardiology·2026
Same author

[Telemonitoring of digital flaps using the Pixacare tool: A prospective implementation study].

Annales de chirurgie plastique et esthetique·2025
Same author

Dissecting the heterogeneity of craniofacial lesions in patients with fibrous dysplasia/McCune-Albright Syndrome.

International journal of oral and maxillofacial surgery·2024
Same author

Standards for clinical trials for treating TB.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2023
Same author

Microvascular arterial disease of the brain and the heart: a shared pathogenesis.

QJM : monthly journal of the Association of Physicians·2023
Same author

Prevention and early treatment of the long-term physical effects of COVID-19 in adults: design of a randomised controlled trial of resistance exercise-CISCO-21.

Trials·2022

Area of Science:

  • Cardiovascular Physiology
  • Renal Physiology
  • Hypertension Research

Background:

  • Dietary salt intake significantly impacts blood pressure regulation.
  • Salt sensitivity, the variability in blood pressure response to salt, is a key factor in hypertension.
  • Understanding factors influencing salt sensitivity is crucial for effective hypertension management.

Purpose of the Study:

  • To investigate the prevalence and predictors of salt sensitivity in men.
  • To examine the effects of high versus low sodium intake on blood pressure and hormonal responses.
  • To determine if race, diagnosis, or obesity influence salt sensitivity.

Main Methods:

  • Seventy-five men (hypertensive vs. normotensive, Black vs. White) underwent a crossover study.
  • Participants were fed diets with high (200 mEq/day) and low (10 mEq/day) sodium intake.
  • Blood pressure, plasma norepinephrine, and renin levels were measured under both dietary conditions.

Main Results:

  • High salt intake decreased diastolic pressure in all groups.
  • Systolic pressure increased with high salt in hypertensive individuals, especially Black hypertensives.
  • Obesity and blunted reductions in norepinephrine/renin during salt loading predicted increased systolic pressure.

Conclusions:

  • Systolic salt sensitivity is influenced by race, hypertension status, obesity, and hormonal responses.
  • The findings question the universal recommendation of low-salt diets for all hypertensive patients.
  • Personalized dietary salt strategies may be necessary for optimal blood pressure control.

Related Experiment Videos