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Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients
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Published on: June 11, 2011

Tuberculosis of the central nervous system in immunocompromised patients: HIV infection and solid organ transplant

Christina A Nelson1, Joseph R Zunt

  • 1Department of Neurology, Global Health, Medicine, and Epidemiology, University of Washington School of Medicine, Seattle, Washington, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|October 1, 2011
PubMed

Central nervous system (CNS) tuberculosis (TB) is a devastating infection with high rates of morbidity and mortality worldwide and may manifest as meningitis, tuberculoma, abscess, or other forms of disease. Immunosuppression, due to either human immunodeficiency virus infection or solid organ transplantation, increases susceptibility for acquiring or reactivating TB and complicates the management of underlying immunosuppression and CNS TB infection. This article reviews how immunosuppression alters the clinical presentation, diagnosis, treatment, and outcome of TB infections of the CNS.

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