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Related Concept Videos

Menopause01:28

Menopause

Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
Cholesterol: Significance and Regulation01:29

Cholesterol: Significance and Regulation

Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Signs of Puberty01:27

Signs of Puberty

Puberty is a critical phase, typically beginning between the ages of 8 and 13 in girls and 9 and 14 in boys, though timing can vary based on genetics, environmental factors, and overall health. This period is characterized by the development of secondary sexual characteristics and the attainment of reproductive potential. Endocrine changes underpin puberty, with hormonal surges of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) instigated by Gonadotropin-Releasing Hormone (GnRH)...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Hypodermis01:02

Hypodermis

The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.

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Athletic activity and hormone concentrations in high school female athletes.

Journal of athletic training·2014
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The adipokine profile of metabolically benign obese and at-risk normal weight postmenopausal women: the Women's Health Initiative Observational Study.

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Effect of modest changes in BMI on cardiovascular disease risk markers in severely obese, minority adolescents.

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Changes in bone resorption across the menopause transition: effects of reproductive hormones, body size, and ethnicity.

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Related Experiment Video

Updated: May 28, 2026

Isolation and Culturing of Primary Murine Adipocytes from Lean and Obese Mice
05:34

Isolation and Culturing of Primary Murine Adipocytes from Lean and Obese Mice

Published on: January 24, 2025

Adiposity and the menopausal transition.

Rachel P Wildman1, MaryFran R Sowers

  • 1Department of Epidemiology & Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA. rachel.wildman@einstein.yu.edu

Obstetrics and Gynecology Clinics of North America
|October 4, 2011
PubMed
Summary

Obesity impacts menopause hormone changes and chronic disease risk. However, the menopause transition

Area of Science:

  • Reproductive Endocrinology
  • Metabolic Health
  • Women's Health

Background:

  • The menopause transition involves significant hormonal shifts.
  • Adiposity is a growing public health concern.
  • Understanding the interplay between obesity and menopause is crucial for women's health.

Purpose of the Study:

  • To review existing literature on the relationship between adiposity and menopause.
  • To examine how obesity influences menopausal hormone changes.
  • To assess the impact of menopause on body composition and weight.

Main Methods:

  • Literature review of published studies.
  • Synthesis of data on adiposity, hormone levels, and menopausal symptoms.
  • Analysis of research investigating weight changes during menopause.

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Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
08:34

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

Published on: June 3, 2016

Related Experiment Videos

Last Updated: May 28, 2026

Isolation and Culturing of Primary Murine Adipocytes from Lean and Obese Mice
05:34

Isolation and Culturing of Primary Murine Adipocytes from Lean and Obese Mice

Published on: January 24, 2025

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
08:34

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

Published on: June 3, 2016

Main Results:

  • Obesity and adiposity significantly affect hormone level changes during menopause.
  • Increased adiposity is linked to altered hormone profiles during the menopausal transition.
  • Evidence suggests obesity influences chronic disease risk post-menopause.

Conclusions:

  • Adiposity plays a substantial role in modulating menopausal hormone changes and associated health risks.
  • The influence of menopause on weight gain and fat redistribution remains inconclusive.
  • Further research is needed to clarify the bidirectional relationship between adiposity and menopause.