Related Experiment Video

Updated: May 28, 2026

Clinicopathological Analysis of miRNA Expression in Breast Cancer Tissues by Using miRNA In Situ Hybridization
06:01

Clinicopathological Analysis of miRNA Expression in Breast Cancer Tissues by Using miRNA In Situ Hybridization

Published on: June 7, 2016

Single nucleotide polymorphism in hsa-mir-196a-2 and breast cancer risk: a case control study

Dominik J Jedlinski1, Plamena N Gabrovska, Stephen R Weinstein

  • 1Griffith Health Institute, Griffith University Gold Coast, Southport, Australia.

Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies
|October 4, 2011
PubMed

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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