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Variability and specificity associated with environmental methamphetamine sampling and analysis.

Mike V Van Dyke¹, Kate A Serrano, Shalece Kofford

¹Department of Environmental and Occupational Health Sciences, National Jewish Health, Denver, Colorado 80206, USA.

Journal of Occupational and Environmental Hygiene

|October 4, 2011

Summary

This summary is machine-generated.

Wipe sampling effectively detects methamphetamine contamination from clandestine labs. Methanol and isopropanol are suitable solvents, and common household substances do not cause false positives.

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Area of Science:

Forensic Science
Environmental Chemistry

Background:

Clandestine methamphetamine manufacture poses significant contamination risks.
Accurate detection of methamphetamine residues is crucial for remediation and safety.

Purpose of the Study:

To evaluate the efficacy of wipe sampling for detecting methamphetamine contamination.
To assess laboratory variability and the impact of different sampling parameters on results.

Main Methods:

Analyzed spiked wipe samples across three laboratories using liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS).
Investigated the effect of different sampling media, surfaces, solvents (methanol, isopropanol), and common household contaminants.
Assessed false positive rates using blank samples.

Main Results:

Laboratory variability in methamphetamine concentration analysis ranged from 3-30%.
Methanol and isopropanol demonstrated comparable recovery rates for methamphetamine.
Dust and paint contaminants did not interfere with methamphetamine detection.
No false positive detections were observed in blank samples.

Conclusions:

Wipe sampling is a reliable method for determining methamphetamine contamination.
Methanol and isopropanol are appropriate solvents for methamphetamine wipe sampling.
The method is robust against common interferences and provides accurate results in methamphetamine-free structures.