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Updated: May 28, 2026

Fluorescent Lateral Flow Immunoassay Based on Quantum Dots Nanobeads
Published on: June 28, 2024
Quantum dot-enhanced chemiluminescence detection for simultaneous determination of dopamine and epinephrine by
Yunsha Zhao1, Shulin Zhao, Junming Huang
1Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education), College of Chemistry and Chemical Engineering, Guangxi Normal University, Guilin, 541004, China.
Abstract:
A sensitive method based on quantum dot (QD)-enhanced capillary electrophoresis-chemiluminescence (CE-CL) detection was developed for simultaneous determination of dopamine (DA) and epinephrine (E). In this work, CdTe QD was added into the running buffer of CE to catalyze the post-column CL reaction between luminol and hydrogen peroxide, achieving higher CL emission. Negative peaks were produced due to the inhibitory effects on CL emission from DA and E eluted from the electrophoretic capillary. The decrease in CL intensity was proportional to the concentration of DA and E in the range of 8.0 × 10(-8)-5.0 × 10(-6)M and 4.0 × 10(-8)-5.0 × 10(-6)M, respectively. Detection limits for DA and E were 2.3 × 10(-8)M and 9.3 × 10(-9)M, respectively. Using this method, the levels of DA and E in human urine from healthy donors were determined.
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