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Related Concept Videos

Spermatogenesis01:41

Spermatogenesis

Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male reproductive...
Overview of the Reproductive System01:31

Overview of the Reproductive System

The reproductive system generates offspring, ensuring the survival of the species. In humans, the reproductive system is complex and involves a variety of organs and hormones that work together to ensure successful reproduction.
The gonads, or primary reproductive organs, produce gametes and sex hormones. In males, the testes produce spermatozoa and testosterone, which is responsible for developing secondary male sex characteristics, including a deeper voice, larger muscles, facial and body...
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
Infertility in Females01:28

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of endometrial...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

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Comprehensive Assessment of Germline Chemical Toxicity Using the Nematode Caenorhabditis elegans
10:55

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Published on: February 22, 2015

Selenium in reproductive health.

Hiten D Mistry1, Fiona Broughton Pipkin, Christopher W G Redman

  • 1Maternal and Fetal Research Unit, Division of Women's Health, King's College London, United Kingdom. hiten.mistry@kcl.ac.uk

American Journal of Obstetrics and Gynecology
|October 4, 2011
PubMed
Summary
This summary is machine-generated.

Selenium, an essential trace mineral, is vital for human health and reproduction. Selenium deficiency is linked to reproductive issues, but more research is needed to confirm benefits of supplementation.

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Area of Science:

  • Nutritional Science
  • Human Biology
  • Reproductive Health

Background:

  • Selenium is an essential trace element crucial for human health and biological functions.
  • Dietary selenium intake is often below recommended levels, impacting selenoenzyme activity.
  • Low selenium status is associated with various reproductive and obstetric complications.

Purpose of the Study:

  • To review the biological functions of selenium.
  • To examine the association between selenium status and reproductive health.
  • To assess the need for further research on selenium supplementation for reproductive disorders.

Main Methods:

  • Literature review of biological functions of selenium.
  • Systematic review of studies linking selenium status to reproductive health outcomes.
  • Analysis of existing intervention studies on selenium supplementation.

Main Results:

  • Selenium plays a key role in normal growth and reproduction.
  • Deficiency is implicated in infertility, miscarriage, preeclampsia, fetal growth restriction, preterm labor, gestational diabetes, and obstetric cholestasis.
  • Current evidence from small intervention studies is insufficient to guide public health strategies.

Conclusions:

  • Selenium is critical for reproductive health.
  • Further large-scale intervention trials are necessary to establish the efficacy of selenium supplementation in managing reproductive and obstetric complications.