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Related Concept Videos

Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...

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Related Experiment Video

Updated: May 28, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

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[Inflammatory pseudotumor in a five-year-old girl].

M Fernández del Castillo Ascanio1, C González González, S Pascual Pérez

  • 1Servicio de Radiodiagnóstico, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, España. esp272@hotmail.com

Radiologia
|October 4, 2011
PubMed
Summary

Inflammatory pseudotumors are common pediatric lung masses that can resemble pneumonia on imaging. These rare, quasi-neoplastic growths can occur anywhere, mimicking malignant tumors.

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Area of Science:

  • Pediatric Pathology
  • Radiology
  • Oncology

Background:

  • Inflammatory pseudotumors represent the most frequent primary lung mass in pediatric patients.
  • These lesions share imaging characteristics with organizing pneumonia, complicating diagnosis.
  • While commonly affecting the orbit, inflammatory pseudotumors exhibit widespread potential body distribution.

Observation:

  • Inflammatory pseudotumors present a diagnostic challenge due to their quasi-neoplastic behavior.
  • Radiological and clinical presentations often mimic those of malignant tumors.
  • The condition's pathogenesis, natural history, imaging features, and treatment remain subjects of ongoing research and debate.

Findings:

  • The study highlights the frequent misinterpretation of inflammatory pseudotumors as organizing pneumonia in pediatric lung imaging.
  • It underscores the broad anatomical distribution of these masses beyond the lung and orbit.
  • The quasi-neoplastic nature necessitates differential diagnosis from malignancies.

Implications:

  • Accurate identification of inflammatory pseudotumors is crucial for appropriate pediatric patient management.
  • Further research into pathogenesis and natural history may refine diagnostic and therapeutic strategies.
  • Standardized guidelines for imaging and treatment are needed to address diagnostic uncertainties.