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Updated: May 28, 2026

Detection of Histone Modifications in Plant Leaves
Published on: September 23, 2011
Structural basis for cytokinin recognition by Arabidopsis thaliana histidine kinase 4
Michael Hothorn1, Tsegaye Dabi, Joanne Chory
1Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, USA.
Abstract:
Cytokinins are classic hormones that orchestrate plant growth and development and the integrity of stem cell populations. Cytokinin receptors are eukaryotic sensor histidine kinases that are activated by both naturally occurring adenine-type cytokinins and urea-based synthetic compounds. Crystal structures of the Arabidopsis thaliana histidine kinase 4 sensor domain in complex with different cytokinin ligands now rationalize the hormone-binding specificity of the receptor and may spur the design of new cytokinin ligands.
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