Related Experiment Video
Updated: May 28, 2026
09:29
Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
Published on: March 20, 2020
Mouse models of triple negative [basal-like/claudin low] breast cancer
Jason I Herschkowitz1, Ron Lubet
1Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA. herschko@bcm.edu
Breast Disease
|October 4, 2011
Abstract:
Triple negative breast cancer encompasses the molecular subtypes of basal-like and the more recently defined claudin-low group. In this review, we discuss the identification and characterization of mouse models that mimic these human subtypes. These mouse models serve as useful tools for the study of disease biology and represent a valuable resource for the evaluation of experimental therapeutics.
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