A forgotten disease reminds itself with a rare complication

Area of Science:

• Dermatology
• Infectious Diseases
• Oncology

Background:

• Sexually transmitted diseases (STDs) are often underdiagnosed, with Donovanosis being a prime example.
• Donovanosis diagnosis typically relies on identifying Donovan bodies in tissue samples.
• Squamous cell carcinoma is an extremely rare complication of Donovanosis.

Purpose of the Study:

• To highlight the rare occurrence of squamous cell carcinoma in an 18-year-old with Donovanosis.
• To review the current status of Donovanosis as an STD.
• To emphasize the importance of timely treatment for Donovanosis to prevent severe complications.

Main Methods:

• Case report of an 18-year-old female with Donovanosis and subsequent squamous cell carcinoma.
• Review of clinical presentation, diagnostic methods (histology, cytology for Donovan bodies), and treatment outcomes.
• Literature review on the association between Donovanosis and squamous cell carcinoma.

Main Results:

• The case presented an unusual complication of Donovanosis with squamous cell carcinoma in a young patient.
• Donovanosis confirmation was achieved through demonstration of Donovan bodies.
• The case underscores the potential for severe outcomes if Donovanosis is left untreated.

Conclusions:

• Donovanosis, though often clinically apparent, requires histological confirmation.
• The co-occurrence of Donovanosis and squamous cell carcinoma is exceptionally rare but clinically significant.
• Aggressive management of Donovanosis is essential to mitigate risks of complications and improve patient outcomes.