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Related Concept Videos

Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
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Long-term Depression01:05

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Related Experiment Video

Updated: May 28, 2026

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
08:42

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Published on: May 19, 2015

Memory in depression.

S Chandra1, A K Agarwal

  • 1M.O. Incharge, Mental Health Clinic, G.S.V.M. Medical College, Kanpur.

Indian Journal of Psychiatry
|October 4, 2011
PubMed
Summary
This summary is machine-generated.

Depression significantly impairs memory performance, with mental control being the most affected function. Recovery from depression leads to improved memory scores, highlighting a strong negative correlation between depression severity and memory function.

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Related Experiment Videos

Last Updated: May 28, 2026

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
08:42

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Published on: May 19, 2015

Animal Models of Depression - Chronic Despair Model (CDM)
05:47

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Transcranial Direct Current Stimulation (tDCS) for Memory Enhancement
10:37

Transcranial Direct Current Stimulation (tDCS) for Memory Enhancement

Published on: September 18, 2021

Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Psychology

Background:

  • Depression is a common mental health disorder associated with cognitive deficits.
  • Memory impairment is frequently reported in individuals with depression.
  • Understanding the specific impact of depression on memory is crucial for effective treatment.

Purpose of the Study:

  • To assess memory performance in patients with depression.
  • To compare memory scores of depressed individuals with healthy controls.
  • To evaluate the effect of depression treatment on memory function.

Main Methods:

  • 33 patients diagnosed with depression were assessed for memory performance.
  • Memory scores were compared between depressed patients, healthy controls, and patients after recovery.
  • Correlation between depression severity and memory function was analyzed.

Main Results:

  • Depressed patients exhibited significantly poorer memory scores compared to healthy controls.
  • Memory performance improved significantly after successful depression treatment.
  • A significant negative correlation was observed between depression severity and memory scores.
  • The mental control sub-function of memory was most sensitive to depressive symptoms.

Conclusions:

  • Depression has a substantial negative impact on memory function, particularly on mental control.
  • Treatment-induced recovery from depression is associated with significant memory improvement.
  • Memory deficits in depression are likely reversible with effective therapeutic interventions.