Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Structural Isomerism02:34

Structural Isomerism

Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula. Structural isomerism of coordination compounds can be divided into two subcategories, the linkage isomers and coordination-sphere isomers.
Linkage isomers occur when the coordination compound contains a ligand that can bind to the transition metal center through two different atoms. For example, the CN− ligand can bind through the carbon atom or through the nitrogen atom. Similarly, SCN− can be...
Coordination Number and Geometry02:57

Coordination Number and Geometry

For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar.
Metal-Ligand Bonds02:51

Metal-Ligand Bonds

The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
Valence Bond Theory02:42

Valence Bond Theory

Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
Coordination Compounds and Nomenclature02:54

Coordination Compounds and Nomenclature

In most main group element compounds, the valence electrons of the isolated atoms combine to form chemical bonds that satisfy the octet rule. For instance, the four valence electrons of carbon overlap with electrons from four hydrogen atoms to form CH4. The one valence electron leaves sodium and adds to the seven valence electrons of chlorine to form the ionic formula unit NaCl (Figure 1a). Transition metals do not normally bond in this fashion. They primarily form coordinate covalent bonds, a...
Stereoisomerism02:52

Stereoisomerism

Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Designing inhalable amorphous solid dispersions to mitigate crystallization risks in atropisomer development.

International journal of pharmaceutics·2026
Same author

Engineering the Thermometric Response of Dinuclear Eu<sup>III</sup> Complexes via Terminal Ligand-Induced Nonradiative Processes.

ACS omega·2026
Same author

Metal-Dependent Photodissociation of Hydrazone Photoswitches from Rare-Earth Complexes.

Journal of the American Chemical Society·2026
Same author

Beyond-Kasha Photochemistry in a Heteroleptic Platinum-Dithiolene Complex.

Journal of the American Chemical Society·2026
Same author

Design, Synthesis, and Biological Evaluation of the Novel Neutrophil Elastase Inhibitor CHF-6333 for the Inhaled Treatment of Bronchiectasis.

Journal of medicinal chemistry·2025
Same author

Polynuclear Complexes of Nd and Dy with N<sub>2</sub>O<sub>3</sub> Donor Ligands: Solution Speciation and Selective Precipitation Studies.

Inorganic chemistry·2025

Related Experiment Video

Updated: May 28, 2026

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
12:30

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework

Published on: April 9, 2018

Structural variability in Ag(I) and Cu(I) coordination polymers with thioether-functionalized bis(pyrazolyl)methane

Irene Bassanetti1, Luciano Marchiò

  • 1Dipartimento di Chimica Generale ed Inorganica, Chimica Analitica, Chimica Fisica, Università degli Studi di Parma, parco Area delle Scienze 17/a, I 43124 Parma, Italy.

Inorganic Chemistry
|October 5, 2011
PubMed
Summary

New bis(pyrazolyl)methane ligands with thioether functions were synthesized and characterized. These ligands form coordination polymers and mononuclear complexes with silver(I) and copper(I) metals.

More Related Videos

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

Synthesis of Triazole and Tetrazole-Functionalized Zr-Based Metal-Organic Frameworks Through Post-Synthetic Ligand Exchange
04:51

Synthesis of Triazole and Tetrazole-Functionalized Zr-Based Metal-Organic Frameworks Through Post-Synthetic Ligand Exchange

Published on: June 23, 2023

Related Experiment Videos

Last Updated: May 28, 2026

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
12:30

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework

Published on: April 9, 2018

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

Synthesis of Triazole and Tetrazole-Functionalized Zr-Based Metal-Organic Frameworks Through Post-Synthetic Ligand Exchange
04:51

Synthesis of Triazole and Tetrazole-Functionalized Zr-Based Metal-Organic Frameworks Through Post-Synthetic Ligand Exchange

Published on: June 23, 2023

Area of Science:

  • Coordination Chemistry
  • Supramolecular Chemistry
  • Materials Science

Background:

  • Bis(pyrazolyl)methane scaffolds are versatile building blocks in coordination chemistry.
  • Thioether functionalization offers opportunities for diverse coordination modes.
  • Understanding ligand flexibility is crucial for designing coordination polymers and complexes.

Purpose of the Study:

  • To synthesize and characterize two new classes of bis(pyrazolyl)methane ligands with rigid and flexible thioether moieties.
  • To investigate the coordination behavior of these ligands with Ag(I) and Cu(I) ions.
  • To explore the structural diversity of resulting binary and ternary complexes, including coordination polymers.

Main Methods:

  • Synthesis of bis(pyrazolyl)methane ligands functionalized with rigid (-Ph-S-Ph) or flexible (-CH(2)-S-Ph) thioether groups.
  • X-ray crystallography to determine the molecular structures of Ag(I) and Cu(I) complexes.
  • Density Functional Theory (DFT) calculations to analyze ligand conformational preferences.

Main Results:

  • Two ligand classes, L(R)PhS (rigid) and L(R)CH(2)S (flexible), were successfully synthesized.
  • Binary complexes showed bridging coordination via N(2) and thioether groups, forming coordination polymers.
  • Ternary complexes with triphenylphosphine revealed N(2)S chelation for the flexible ligand and only N(2) coordination for the rigid ligand.

Conclusions:

  • Both ligand classes are suitable for constructing coordination polymers.
  • The flexible L(R)CH(2)S ligand class enables N(2)S chelation due to accessible conformations.
  • The rigid L(R)PhS ligand class primarily exhibits N(2) coordination due to preorganized thioether orientation.