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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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Evaluation of left atrial function in patients with coronary artery disease by two-dimensional strain and strain rate

Ying-ying Liu1, Ming-xing Xie, Jin-feng Xu

  • 1Department of Ultrasonography, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Echocardiography (Mount Kisco, N.Y.)
|October 5, 2011
PubMed

Insights

Left atrial (LA) diastolic dysfunction precedes systolic dysfunction in coronary artery disease (CAD) patients. Two-dimensional strain echocardiography (2DSE) effectively identifies CAD, with LA strain rate (LAs SR) being the most accurate indicator.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Imaging

Background:

  • Left ventricular (LV) dysfunction in coronary artery disease (CAD) is well-established using strain imaging.
  • Left atrial (LA) function in CAD patients has not been extensively evaluated with strain and strain rate imaging.

Purpose of the Study:

  • To assess left atrial (LA) function in patients with coronary artery disease (CAD) using two-dimensional strain echocardiography (2DSE).
  • To determine the diagnostic accuracy of LA strain parameters in identifying CAD patients.

Main Methods:

  • Two-dimensional strain echocardiographic imaging (2DSE) was performed on 34 CAD patients and 20 healthy controls.
  • Patients were categorized into enlarged LA (ELA) and normal-size LA (NLA) groups.
  • Measurements included conventional parameters and LA strain parameters: LA peak systolic strain (LAs S/SR), preatrial contraction strain (LAa S), peak systolic (LAs SR), early diastolic strain rate (LAe SR), and late diastolic strain rate (LAa SR).

Main Results:

  • Conventional parameters were abnormal only in the ELA group, while strain parameters were reduced in all CAD patients compared to controls.
  • LA diastolic dysfunction (reduced LAe SR) and systolic dysfunction (reduced LAs S/SR, LAa S/SR) were evident in CAD patients, particularly those with ELA.
  • LA strain rate (LAs SR) demonstrated the highest accuracy (AUC 0.91-0.95) in differentiating CAD patients from controls and NLA patients from controls.

Conclusions:

  • Left atrial (LA) diastolic dysfunction occurs before LA systolic dysfunction in patients with coronary artery disease (CAD).
  • LA strain rate (LAs SR) is the most accurate echocardiographic index for identifying patients with CAD.
Abstract

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