Biologic response modifiers: the future of cancer therapy?

The major shift today has been away from nonspecific compounds acting on immune mechanisms to using biologics which have specific, defined roles in acting on the immune response. The field of biologic response modification is progressing very rapidly. New peptides are being identified, as are receptors for these peptides, autocrines, lymphokines, cytokines, growth factors, differentiation factors, hormones, and so on-all of which will control body function, cell populations, and cell to cell interactions. This rapidly advancing area of research in cancer biology and cancer therapy may hold the key to the future of successful therapy.