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Related Experiment Videos

Deciduosis of the appendix.

S Suster1, C A Moran

  • 1Department of Pathology, Yale University School of Medicine, New Haven, Connecticut.

The American Journal of Gastroenterology
|July 1, 1990
PubMed
Summary
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Deciduosis of the appendix, a rare condition in pregnant women, can mimic appendicitis symptoms. This study examines six cases, revealing decidualized cells in the appendix serosa, potentially causing peritoneal irritation.

Area of Science:

  • Reproductive Medicine
  • Gastroenterology Pathology
  • Surgical Pathology

Background:

  • Deciduosis, characterized by ectopic decidual tissue, is a known phenomenon during pregnancy.
  • Appendiceal involvement is rare, and its clinical significance, particularly in mimicking acute appendicitis, requires further investigation.

Observation:

  • Six cases of appendiceal deciduosis in pregnant women (ages 18-40) were studied.
  • Four patients presented with symptoms suggestive of acute appendicitis between the 26th and 31st weeks of gestation.
  • Two cases were incidental findings during cesarean sections or tubal ligations at term.

Findings:

  • Histological examination revealed subepithelial decidualized cell deposits in the appendix serosa.
  • Immunohistochemistry confirmed the stromal origin of these cells, with strong vimentin expression.

Related Experiment Videos

  • Coexpression of vimentin and desmin in two cases suggested myoid differentiation.

    • Implications:

    • Appendiceal deciduosis can present as acute appendicitis in pregnant patients, necessitating careful differential diagnosis.
    • Understanding the immunohistochemical profile aids in distinguishing deciduosis from other appendiceal pathologies.
    • This condition highlights the potential for ectopic decidual tissue to cause abdominal symptoms during pregnancy.