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Related Concept Videos

Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
Nonlinear Pharmacokinetics: Overview01:19

Nonlinear Pharmacokinetics: Overview

Nonlinear or dose-dependent pharmacokinetics is a phenomenon that occurs when the pharmacokinetic parameters of certain drugs deviate from linear pharmacokinetics at higher doses. These drugs do not follow the expected first-order kinetics, where the rate of drug elimination is directly proportional to the drug concentration. Instead, they exhibit a nonlinear relationship, which can be attributed to several factors.
Nonlinearity can arise due to the saturation of plasma protein-binding or...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...

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A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Educating for safety in the pharmacy curriculum.

Eleanor M Vogt1, Daniel C Robinson, Shelley L Chambers-Fox

  • 1University of California San Francisco School of Pharmacy, Campus Box 0613, 3333 California St., Suite 420E, San Francisco, CA 94118, USA. vogte@pharmacy.ucsf.edu

American Journal of Pharmaceutical Education
|October 5, 2011
PubMed
Summary

This issue addresses unsafe patient care and highlights strategies for enhancing healthcare safety and quality. It emphasizes the crucial role of pharmacy education in promoting medication safety and improving patient outcomes.

Keywords:
curriculummedication safetypatient safetyquality improvement

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Area of Science:

  • Healthcare Education
  • Patient Safety
  • Medication Management

Background:

  • Unsafe patient care presents a significant and urgent problem in healthcare.
  • Previous research has identified key learnings for improving healthcare safety and quality.
  • Educators need to understand the implications of these findings for curriculum development.

Purpose of the Study:

  • To explore the context and urgency of unsafe care.
  • To review advancements in improving healthcare safety and quality.
  • To determine the implications for health professions educators, particularly in pharmacy.

Main Methods:

  • This is an overview of a supplement issue.
  • It synthesizes existing knowledge and task force recommendations.
  • It focuses on the role of pharmacy education in patient safety.

Main Results:

  • The supplement issue responds to a directive from the American Association of Colleges of Pharmacy (AACP) Councils.
  • It addresses the national patient safety agenda concerning medication safety.
  • It aims to guide pharmacy schools in curriculum development and best practices.

Conclusions:

  • Pharmacy education must actively engage with the national patient safety agenda.
  • Developing curricula focused on medication safety is essential.
  • Promoting best practices in medication safety is a key responsibility for pharmacy educators.