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[Lidocaine aerosol following tonsillectomy in children]
1Département d'Anesthésie-Réanimation, Hôpital du St-Sacrement, Université Laval, Québec.
Insights
Topical aerosol lidocaine provided superior immediate pain relief after tonsillectomy compared to intramuscular codeine in children. This analgesic technique demonstrated improved postoperative comfort without increasing recovery time.
Area of Science:
- Anesthesiology
- Pediatric Surgery
- Pain Management
Background:
- Post-tonsillectomy pain is a significant concern affecting pediatric recovery.
- Current analgesia methods, like intramuscular codeine, have limitations in immediate efficacy.
- Novel pain management strategies are needed for effective post-surgical pain control.
Purpose of the Study:
- To compare the efficacy of topical aerosol lidocaine versus intramuscular codeine for post-tonsillectomy pain management in children.
- To evaluate the immediate postoperative comfort and recovery times associated with each analgesic method.
- To assess the safety profile of aerosol lidocaine by monitoring systemic concentrations.
Main Methods:
- A randomized study involving 30 children (2-10 years) undergoing tonsillectomy.
- Group A received 1.5 mg/kg intramuscular codeine; Group B received 4 mg/kg topical aerosol lidocaine applied to tonsillar beds.
- Postoperative comfort was assessed using a global scale, and blood lidocaine levels were monitored.
Main Results:
- Topical aerosol lidocaine demonstrated statistically superior immediate postoperative comfort compared to intramuscular codeine.
- Systemic lidocaine concentrations remained well below toxic levels (maximal 2.1 ± 0.2 µg/mL vs. toxic level of 5.3 µg/mL).
- There was no statistically significant difference in recovery room times between the two groups.
Conclusions:
- Topical aerosol lidocaine (4 mg/kg) is a superior immediate analgesic technique for post-tonsillectomy pain in children.
- This method offers effective pain relief without compromising patient safety or prolonging recovery.
- Aerosol lidocaine presents a promising alternative for immediate post-tonsillectomy pain management.
Abstract:
Post-tonsillectomy analgesia was compared using ten per cent aerosol lidocaine or 1.5 mg.kg-1 intramuscular codeine. Thirty ASA physical status I or II children between two and ten years of age were assigned, in a random fashion, to one of two groups: Group A received codeine 1.5 mg.kg-1 intramuscularly, Group B received a total dose of 4 mg.kg-1 of ten per cent aerosol lidocaine on the tonsillar beds. For both groups, the treatment was administered at the end of the surgical procedure. The postoperative comfort state was assessed on a global scale using the following statement: (1) comfortable = 1, (2) agitation = 2, (3) uncontrollable = 3. Assessment of postoperative comfort was recorded after 20 min in the post-anaesthetic recovery room. Blood samples for lidocaine concentration estimation were obtained at 5, 7.5, 10, and 15 min after administration. Finally, the time of recovery was recorded. The immediate post-anaesthetic comfort observed with ten per cent aerosol lidocaine was statistically superior to that obtained with 1.5 mg.kg-1 intramuscular codeine. The maximal systemic lidocaine concentration which was 2.1 +/- 0.2 micrograms.ml-1 was well below the accepted toxic level of 5.3 micrograms.ml-1. The recovery room times were not statistically different between the two groups. In conclusion, 4 mg.kg-1 of ten per cent aerosol lidocaine applied directly on the tonsillar beds was shown a superior immediate post-tonsillectomy analgesic technique.
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