Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypersensitive teeth. Experimental studies of dentinal desensitizing agents.

K Markowitz1, S Kim

  • 1Division of Endodontics, School of Dental and Oral Surgery, Columbia University, New York, New York.

Dental Clinics of North America
|July 1, 1990
PubMed
Summary

Potassium nitrate (KNO3) effectively reduces dentinal hypersensitivity by decreasing nerve activity. This desensitizing effect is attributed to the potassium ion

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessing the Appearance and Fluorescence of Resin-Infiltrated White Spot Lesions With Caries Detection Devices.

Operative dentistry·2017
Same author

Human lactoferrin protects against Streptococcus mutans-induced caries in mice.

Oral diseases·2015
Same author

Oral lactoferrin protects against experimental candidiasis in mice.

Journal of applied microbiology·2014
Same author

An overview of children's oral health-related quality of life assessment: from scale development to measuring outcomes.

Caries research·2013
Same author

Lactoferrin knockout mice demonstrates greater susceptibility to Aggregatibacter actinomycetemcomitans-induced periodontal disease.

Journal of periodontology·2013
Same author

The effect of distance and tooth structure on laser fluorescence caries detection.

Operative dentistry·2011

Area of Science:

  • Dentistry
  • Neuroscience
  • Pharmacology

Background:

  • Dentinal hypersensitivity is a common dental issue.
  • Desensitizing agents aim to reduce nerve signaling in dentinal tubules.

Purpose of the Study:

  • To investigate the impact of dentinal desensitizing agents on nerve activity.
  • To identify the mechanisms behind the efficacy of agents like potassium nitrate.

Main Methods:

  • Testing the effect of various dentinal desensitizing agents.
  • Measuring changes in nerve activity in response to these agents.

Main Results:

  • Potassium nitrate (KNO3) was identified as an effective agent.
  • KNO3 significantly reduced dentinal sensory nerve activity.

Related Experiment Videos

Conclusions:

  • Potassium nitrate's efficacy in reducing dentinal hypersensitivity is confirmed.
  • The potassium ion (K+) plays a key role through its depolarizing action on nerve fibers.