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Prospects for specific immunotherapy in myasthenia gravis
1Department of Genetics, Stanford University School of Medicine, California 94305.
Abstract:
Myasthenia gravis is an autoimmune disease resulting from a breakdown in T and B cell tolerance to acetylcholine receptor (AChR). Autoantibodies to AChR mediate the disease. Recent advances in experimental immunotherapy of autoimmune disease provide several possibilities for specific intervention in this well-characterized condition.