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Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
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β-receptor blockers significantly impact the cardiovascular system by counteracting catecholamine-induced sympathetic responses. These medications decrease heart rate, contractility, and cardiac output, potentially leading to cardiac depression, life-threatening bradycardia, and death. Therapeutically, β-blockers function as mild antihypertensives and are utilized in treating angina pectoris and cardiac arrhythmias. However, nonselective β-blockers inhibit β2-receptors in bronchial smooth...
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Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy
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Bilateral thoracic sympathetic block for refractory polymorphic tachycardia.

Frederick Allen1, Brian Weaver, Adam Burkey

  • 1Department of Anesthesiology and Critical Care, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA. fredallenmd@gmail.com

Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie
|October 6, 2011
PubMed
Summary

A novel lytic thoracic sympathetic block offers a less invasive treatment for refractory ventricular tachycardia. This procedure showed clinical improvement with minimal morbidity in a patient with cardiomyopathy.

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Area of Science:

  • Cardiology
  • Pain Medicine
  • Interventional Cardiology

Background:

  • Sympathetic nervous system hyperactivity is linked to ventricular arrhythmias and sudden cardiac death.
  • Cardiac sympathectomy can treat high-risk patients but is invasive.
  • Refractory ventricular tachycardia poses a significant clinical challenge.

Observation:

  • A 74-year-old male with ischemic cardiomyopathy experienced refractory ventricular tachycardia despite maximal medical and interventional therapies.
  • The patient developed sustained ventricular tachycardia requiring vasopressors.
  • An open thoracoscopic sympathectomy was deemed too risky; a lytic thoracic sympathetic block was performed instead.

Findings:

  • The lytic thoracic sympathetic block resulted in a period of clinical improvement for the patient.
  • The procedure was associated with no apparent morbidity.
  • This technique represents a less invasive alternative to traditional cardiac sympathectomy.

Implications:

  • Lytic thoracic sympathetic blockade is a potentially viable, minimally invasive treatment for sympathetically mediated ventricular tachycardia.
  • Further studies are needed to validate this technique for patients at high risk of ventricular ectopy.
  • This case suggests feasibility and low morbidity for refractory ventricular arrhythmias.