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Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
Published on: February 16, 2024
[Galli-Galli disease. Clinical and histopathological investigation using a case series of 18 patients]
S Hanneken1, A Rütten, S Eigelshoven
1Hautklinik, Universitätsklinikum Düsseldorf, Moorenstr. 5, 40225 Düsseldorf. Hanneken@med.uni-duesseldorf.de
Abstract:
Galli-Galli disease, a rare genodermatosis belonging to the spectrum of reticulate pigment dermatoses, is classified as an acantholytic variant of Dowling-Degos disease on the basis of its characteristic clinical and histological findings. In the context of this case series, Galli-Galli disease is characterized in detail based on the clinical and histopathological evaluation of 18 patients. The disease pattern is discussed in view of the current literature. In addition, a classification into two clinical subtypes is made and a genotype/phenotype correlation with mutations in the keratin 5 (KRT5) gene is established.
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