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Updated: May 28, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Paternal postpartum mood: bipolar episodes?

Karen Amaral Tavares Pinheiro¹, Fabio Monteiro da Cunha Coelho, Luciana de Ávila Quevedo

¹Postgraduate Program in Health and Behavior, Universidade Católica de Pelotas, Pelotas, RS, Brazil.

Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999)

|October 6, 2011

Summary

This summary is machine-generated.

Bipolar and depressive episodes are common in fathers during pregnancy and postpartum. Men experiencing depressive symptoms antenatally should be screened for manic and hypomanic symptoms.

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Analysis of Electrocardiograms and Behavior in Mice from Pregnancy to Lactation Period

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Published on: April 5, 2024

Area of Science:

Psychiatry
Maternal and Child Health
Epidemiology

Background:

Paternal mental health is crucial for family well-being.
Limited research exists on paternal bipolar and depressive episodes during the perinatal period.

Purpose of the Study:

To determine the prevalence of depressive and bipolar spectrum episodes in fathers during pregnancy, postpartum, and 12 months after childbirth.
To investigate the association between depressive and manic/hypomanic episodes over time.

Main Methods:

A longitudinal study followed 739 fathers in Pelotas, Brazil.
Paternal psychopathology was assessed using the Mini Neuropsychiatric Interview (MINI) at three time points: antenatal, 30-60 days postpartum, and 12 months postpartum.

Main Results:

Prevalence of depressive episodes was 5.0% (antenatal), 4.5% (postpartum), and 4.3% (12 months).
Mixed episodes accounted for a significant proportion of depression cases, particularly antenatally (61.1%).
Depressive and manic/hypomanic episodes were associated during pregnancy and postpartum, but not at 12 months.

Conclusions:

Bipolar episodes are common in fathers with depressive symptoms during pregnancy and postpartum.
Routine screening for manic and hypomanic symptoms is recommended for this population.
Paternal mental health monitoring is essential throughout the perinatal period.