Confusion and the patient on an intensive topical ocular antibiotic regimen: a case analysis

Round-the-clock instillation of antibiotics disrupts the sleep-wake cycle and may concomitantly result in an acute confusional state. Behavioral manifestations can be attributed to alterations in the sleep-wake cycle; sensory/environmental deficit related to hospitalization; alterations in nutrition and electrolyte balance; age; and medication. Patients at high risk for confusion must be identified and given priority attention. Acute confusion, if not detected and addressed early, may have serious consequences as threatening as the loss of sight.