[Relation between the energy parameters and the free pool of polyamines in Escherichia coli during synchronous...

The cell cycle of Escherichia coli is characterised by synchronous oscillations in the levels of ATP and putrescine. Oscillations in the pool of putrescine are determined by ATP content which exerts a strong stimulating effect on the activity of ornithine decarboxylase, the key enzyme of polyamine synthesis. The results allow one to consider the system of polyamine synthesis as a point in the regulatory interaction (coupling) between the constructive and energetic types of E. coli metabolism.