Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

ER Retrieval Pathway01:45

ER Retrieval Pathway

In the secretory pathway, vesicles transport proteins from one cellular compartment to another in forward transport to deliver the protein to its correct location. Occasionally, misfolded proteins and incorrect proteins escape their original compartments, and a retrieval pathway is used to return the escaped proteins to their original compartment.
The ER uses many checkpoints to prevent the entry of incorrectly folded or a resident protein as cargo onto a transport vesicle. These mechanisms...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

"A chromosome-level reference genome for the colonial marine hydrozoan Podocoryna americana".

G3 (Bethesda, Md.)·2026
Same author

A chromosome-level genome assembly for the colonial marine hydrozoan <i>Podocoryna americana</i>.

bioRxiv : the preprint server for biology·2026
Same author

Genomic signatures of speciation and adaptation in the ctenophore Mnemiopsis.

BMC biology·2026
Same author

A Chromosome-level Assembly and Functional Genomic Resources for the Model Annelid Capitella teleta.

Genome biology and evolution·2026
Same author

An updated and spatially validated somatic single-cell atlas of Hydractinia symbiolongicarpus.

BMC genomics·2025
Same author

A chromosome-level assembly and functional genomic resources for the model annelid <i>Capitella teleta</i>.

bioRxiv : the preprint server for biology·2025

Related Experiment Video

Updated: May 28, 2026

Pattern-based Search of Epigenomic Data Using GeNemo
06:38

Pattern-based Search of Epigenomic Data Using GeNemo

Published on: October 8, 2017

Searching NCBI Databases Using Entrez.

Gretchen Gibney, Andreas D Baxevanis

    Current Protocols in Human Genetics
    |October 7, 2011
    PubMed
    Summary
    This summary is machine-generated.

    The National Center for Biotechnology Information (NCBI) Entrez system simplifies biological data retrieval by leveraging natural connections between database entries. This system allows users to find comprehensive information on biological entities efficiently.

    More Related Videos

    Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
    07:15

    Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

    Published on: January 16, 2019

    Development of Compendium for Esophageal Squamous Cell Carcinoma
    03:36

    Development of Compendium for Esophageal Squamous Cell Carcinoma

    Published on: April 12, 2024

    Related Experiment Videos

    Last Updated: May 28, 2026

    Pattern-based Search of Epigenomic Data Using GeNemo
    06:38

    Pattern-based Search of Epigenomic Data Using GeNemo

    Published on: October 8, 2017

    Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
    07:15

    Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

    Published on: January 16, 2019

    Development of Compendium for Esophageal Squamous Cell Carcinoma
    03:36

    Development of Compendium for Esophageal Squamous Cell Carcinoma

    Published on: April 12, 2024

    Area of Science:

    • Bioinformatics
    • Computational Biology
    • Genomic Data Management

    Background:

    • Biological databases contain numerous interconnected entries.
    • Accessing information across disparate databases is often inefficient.
    • The National Center for Biotechnology Information (NCBI) Entrez system provides a unified interface.

    Purpose of the Study:

    • To describe the NCBI Entrez system for biological information retrieval.
    • To illustrate methods for querying biological databases.
    • To introduce tools for data visualization and query management.

    Main Methods:

    • Utilizing pre-existing biological relationships between database entries.
    • Employing text-based search protocols within the Entrez system.
    • Leveraging built-in Entrez features for advanced querying.
    • Discussing query saving protocols and the Cn3D visualization tool.

    Main Results:

    • Demonstrated efficient retrieval of information on biological entities.
    • Illustrated basic and alternate query protocols for Entrez.
    • Showcased the utility of Entrez for accessing integrated biological data.
    • Highlighted the role of Cn3D in structure visualization.

    Conclusions:

    • The NCBI Entrez system offers a powerful and integrated approach to biological data access.
    • Entrez streamlines the process of information retrieval from multiple public databases.
    • The system supports efficient data exploration through various search and visualization tools.