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Updated: May 28, 2026

Intrafemoral Injection of Human Hematopoietic Stem and Progenitor Cells into Immunocompromised Mice
Published on: December 8, 2023
Hematopoietic cell transplantation for lymphomas
Ernesto Ayala1, Marcie Tomblyn
1Blood and Marrow Transplant Program, Moffitt Cancer Center, Tampa, FL 33612, USA. Ernesto.Ayala@moffitt.org
Background:
The heterogeneity of lymphomas results in numerous treatment options, including both autologous and allogeneic hematopoietic cell transplantation. However, the type of transplantation, the timing the procedure, and the selection of suitable patients for transplant continue to evolve.
Methods:
We reviewed the current medical literature to provide a succinct synthesis for the most common types of lymphoma and the indications for transplantation.
Results:
This review discusses the outcomes of autologous and allogeneic transplantation for patients with diffuse large B-cell lymphoma, follicular lymphoma, HIV-associated lymphomas, mantle cell lymphoma, T-cell lymphoma, and Hodgkin lymphoma.
Conclusions:
Each of these histologies differs in the indications and timing for transplantation. However, ongoing clinical trials support the continuing role of both autologous and allogeneic transplantation for lymphoma management.
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