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Related Concept Videos

Biofilms01:29

Biofilms

Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Microbial Mats01:25

Microbial Mats

Microbial communities forming biofilms and mats represent complex, spatially structured ecosystems where metabolic processes are stratified according to light, oxygen, and nutrient gradients. Biofilms are initial colonization stages, only a few millimeters thick, while mature microbial mats can reach centimeter-scale thickness and display intricate vertical organization. Their structural and functional heterogeneity allows microorganisms to occupy distinct ecological niches within a few...
Microenvironments01:22

Microenvironments

Microorganisms inhabit highly localized spaces known as microenvironments, which are defined by distinct physical and chemical characteristics. These include oxygen concentration, pH, temperature, light availability, and nutrient levels. The conditions within a microenvironment can differ markedly from those in the surrounding area and significantly influence microbial growth, metabolism, and community structure.Microenvironments often display sharp physicochemical gradients over small spatial...
Colonisation of Pathogens01:25

Colonisation of Pathogens

Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...
Introduction to the Human Microbiota01:22

Introduction to the Human Microbiota

Microorganisms colonize various regions of the human body, including the mouth, nasal passages, throat, stomach, intestines, urogenital tract, and skin. The total number of microbial cells is estimated to range from 10¹³ to 10¹⁴—comparable to, or exceeding, the number of human somatic cells. This host–microbiome relationship has led to the conceptualization of humans as supraorganisms, wherein microbial communities perform vital roles in development, immunity, and disease...

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A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
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A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries

Published on: December 27, 2016

Biofilms: A microbial home.

Rita Chandki1, Priyank Banthia, Ruchi Banthia

  • 1Department of Periodontics, Modern Dental College and Research Centre, Indore, Madhya Pradesh, India.

Journal of Indian Society of Periodontology
|October 7, 2011
PubMed
Summary
This summary is machine-generated.

Microbial biofilms are key to dental caries and periodontal disease. Regular disruption of these oral biofilms is essential for preventing and managing these common oral health issues.

Keywords:
Biofilmmicrobesperiodontal disease

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Area of Science:

  • Oral microbiology
  • Dental research
  • Pathogen research

Background:

  • Microbial biofilms are a significant factor in the development of dental caries and periodontal disease.
  • The complex properties of these biofilms present substantial challenges in oral healthcare.
  • Effective prevention and management strategies necessitate regular disruption of microbial biofilms.

Purpose of the Study:

  • To provide a comprehensive overview of microbial biofilms in the context of oral health.
  • To elucidate the properties and etiopathogenesis mechanisms of oral microbial biofilms.
  • To detail the methods for detection and removal of these biofilms.

Main Methods:

  • Literature review and synthesis of existing research on microbial biofilms.
  • Analysis of the role of biofilms in the etiology of oral diseases.
  • Examination of current and emerging techniques for biofilm detection and disruption.

Main Results:

  • Microbial biofilms are central to the initiation and progression of caries and periodontal disease.
  • Understanding biofilm properties is crucial for developing targeted interventions.
  • Various methods exist for detecting and physically or chemically disrupting biofilms.

Conclusions:

  • Continuous and regular disruption of microbial biofilms is imperative for the prevention and management of oral diseases.
  • Further research into biofilm control strategies can improve oral health outcomes.
  • This review consolidates knowledge on biofilm properties, pathogenesis, detection, and removal.