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Updated: May 28, 2026
A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes
Published on: March 25, 2014
T-cell epitope finding on EPHA2 for further glioma vaccine development: An immunomics study
1Wiwanitkit House, Bangkhae, Bangkok, Thailand.
Background:
Glioma is a deadly neurological tumor. For modern management of glioma, glioma vaccinotherapy is the new concept.
Materials And Methods:
Based on present biomedical technique, the identification of T-cell epitopes via MHC mapping can help clarify the inter-relationship of tumor and immune system. This process can be performed using advanced immunoinformatics technique.
Results:
Here, the author performs an immunoinformatics analysis to find alternative epitopes for glioma-related antigen, EPHA2.
Conclusion:
After complete manipulation on EPHA2 molecules, the five best epitopes were derived.
