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Continuous IOP fluctuation recording in normal tension glaucoma patients
Bojan Pajic1, Brigitte Pajic-Eggspuchler, Ivan Haefliger
1Swiss Eye Research Foundation, Eye Clinic ORASIS, Titlisstrasse, Reinach, Switzerland. bpajic@datacomm.ch
Current Eye Research
|October 8, 2011
Summary
Continuous monitoring of intraocular pressure (IOP) fluctuations using a novel sensor revealed individual patient rhythms. This technology shows sensitivity to IOP changes, both daily and in response to glaucoma treatment.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Medical Device Technology
Background:
- Intraocular pressure (IOP) is a key treatable risk factor for progressive glaucoma.
- Continuous IOP monitoring offers a new approach compared to traditional discrete measurements.
Purpose of the Study:
- To evaluate 24-hour IOP fluctuation monitoring with a SENSIMED Triggerfish sensor in normal tension glaucoma patients.
- To assess the clinical utility of this device in both treated and untreated conditions.
Main Methods:
- 24-hour continuous IOP monitoring was conducted twice in five normal tension glaucoma patients.
- Patients were assessed both without IOP-lowering medication and after a period of treatment.
- Continuous recordings were analyzed for diurnal variations, repeatability, and treatment effects.
Main Results:
- Individual and repeatable IOP fluctuation profiles were observed.
- Daytime IOP showed higher variability than nighttime IOP.
- Significant diurnal IOP slopes were noted in untreated patients, with blunted slopes in treated patients.
Conclusions:
- The continuous IOP monitoring device accurately reflects individual IOP patterns.
- The technology is sensitive to changes in IOP rhythms caused by glaucoma medications.
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