Priority issues in occupational cancer research: Ontario stakeholder perspectives

K Hohenadel1, E Pichora, L Marrett

  • 1Occupational Cancer Research Centre, Toronto, Ontario, Canada. karin.hohenadel@cancercare.on.ca

Abstract

Insights

Occupational cancer research priorities include chemical exposures, asbestos, radiation, and pesticides, particularly for miners and construction workers. Insufficient funding and data hinder progress in this vital research area.

Area of Science:

  • Occupational Health
  • Cancer Research
  • Environmental Epidemiology

Background:

  • Workers face exposure to numerous unassessed carcinogens in the workplace.
  • Occupational cancer research has seen a decline, necessitating focused efforts.
  • The Occupational Cancer Research Centre (OCRC) was established to address this research gap in Ontario.

Purpose of the Study:

  • To identify priority issues and stakeholder concerns in occupational cancer research.
  • To inform the development of the OCRC's research agenda.
  • To understand barriers hindering occupational cancer research.

Main Methods:

  • A survey was distributed to a diverse stakeholder community (academic, health care, policy, industry, labour).
  • 177 responses were collected and analyzed.
  • Analysis stratified findings by respondent occupation, workplace exposures, at-risk occupations, and cancer types.

Main Results:

  • Key exposures identified: chemicals, asbestos, electromagnetic fields, pesticides, shift work.
  • High-risk occupations: miners, construction workers, health care workers.
  • Major barriers: insufficient funding and lack of comprehensive exposure data.

Conclusions:

  • Significant need for occupational cancer research in Ontario and globally.
  • Survey results provide crucial direction for the OCRC's future research initiatives.
  • Addressing funding and data gaps is essential for advancing occupational cancer research.

Related Concept Videos

Nursing Ethical Principles II01:27

Nursing Ethical Principles II

Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's cancer...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Levels of Health Promotion and Illness Prevention01:26

Levels of Health Promotion and Illness Prevention

Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...