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Ultrasound Cyclo Plasty in Eyes with Glaucoma
Published on: January 26, 2018
Deep sclerectomy with mitomycin C in eyes with failed glaucoma surgery and pseudophakia
1Department of Ophthalmology, Calderdale and Huddersfield NHS Trust, Huddersfield Royal Infirmary, Huddersfield, UK. anand1604@gmail.com
Eye (London, England)
|October 8, 2011
Summary
Deep sclerectomy with mitomycin C is a safe and effective glaucoma surgery for patients with prior eye surgeries. This procedure significantly lowers intraocular pressure and reduces medication dependence long-term.
Area of Science:
- Ophthalmology
- Glaucoma Surgery
- Surgical Outcomes
Background:
- Previous glaucoma surgery or cataract extraction can complicate subsequent glaucoma management.
- Elevated intraocular pressure (IOP) remains a risk factor for vision loss in these patients.
Purpose of the Study:
- To evaluate the efficacy and safety of deep sclerectomy (DS) combined with intraoperative mitomycin C (MMC) in eyes with a history of failed glaucoma surgery and/or cataract extraction.
- To assess long-term intraocular pressure control and complication rates.
Main Methods:
- A single-surgeon case series included 82 eyes of 82 patients who underwent DS with MMC application.
- Patients had prior cataract extraction and/or glaucoma surgery with pre-operative IOP >18 mm Hg.
- Mitomycin C (0.2 mg/ml) was applied for 2-3 minutes before scleral flap dissection; success was defined as IOP between 6-21 mm Hg without medication.
Main Results:
- Mean follow-up was over 57 months, with 78% completing 3 years.
- Mean IOP significantly decreased from 24.0 mm Hg preoperatively to 13.4 mm Hg at 3 years (P<0.001).
- Glaucoma medication use decreased from 2.0 to 0.3 at 3 years; cumulative success rates were 76% at 3 years.
Conclusions:
- Deep sclerectomy with mitomycin C offers a safe and effective surgical option for managing glaucoma in eyes with prior intraocular surgeries.
- The procedure demonstrates sustained IOP reduction and decreased medication needs.
- While complications like delayed hypotony occurred, overall outcomes were favorable.
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