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Related Concept Videos

Taste Buds and Receptors01:20

Taste Buds and Receptors

Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
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Allergic Reactions

Overview
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
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Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

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Related Experiment Video

Updated: May 28, 2026

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

Living with food allergy.

Lisa Waddell1

  • 1Nottingham CityCare Partnership.

The Journal of Family Health Care
|October 11, 2011
PubMed
Summary

Food allergy affects many young children, but misdiagnosis is common. A thorough allergy-focused history is crucial for accurate diagnosis of food allergy and lactose intolerance.

Area of Science:

  • Pediatrics
  • Allergology
  • Gastroenterology

Background:

  • Food allergy is a prevalent condition in young children, affecting 6-8% of those under three.
  • Self-diagnosis and lack of professional awareness can lead to malnutrition and other health issues.
  • Conditions like eczema, chronic diarrhea, and reflux may be linked to food allergies.

Purpose of the Study:

  • To highlight the importance of accurate food allergy diagnosis in children.
  • To inform about recent NICE guidelines for improving food allergy diagnosis.
  • To differentiate between food allergy and lactose intolerance.

Main Methods:

  • Emphasizes the role of a detailed allergy-focused clinical history.
  • Includes differentiating between immediate (IgE-mediated) and delayed (non-IgE-mediated) reactions.

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Last Updated: May 28, 2026

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

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  • Considers lactose intolerance as a non-allergic hypersensitivity.

    • Main Results:

    • Accurate diagnosis is essential to prevent malnutrition and other complications.
    • NICE guidelines aim to improve community-level diagnosis of food allergies.
    • Distinguishing between allergic and non-allergic hypersensitivity is key.

    Conclusions:

    • A comprehensive clinical history is the primary tool for diagnosing food allergy and lactose intolerance.
    • Increased awareness among health professionals is needed.
    • Proper diagnosis ensures appropriate management and prevents adverse health outcomes.