The standard range of peak expiratory flow rates of Korean children

Won Hee Seo1, So Hyun Ahn, Su Hwa Park

  • 1Department of Pediatrics, Korea University College of Medicine, Seoul, Korea.

Insights

This study established peak expiratory flow rate (PEFR) reference ranges for Korean children aged 4-18. These new PEFR values, based on height and body surface area, aid asthma management in Korean pediatric patients.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Clinical Pediatrics

Background:

  • Monitoring peak expiratory flow rate (PEFR) is crucial for effective asthma management.
  • Establishing accurate reference ranges is essential for interpreting PEFR measurements in specific populations.

Purpose of the Study:

  • To establish normative reference ranges for PEFR in Korean children aged 4-18 years.
  • To provide percentile curves for PEFR as a function of height for clinical use in Korea.

Main Methods:

  • Utilized the Mini Wright Peak Flow Meter (MWPFM) and spirometry.
  • Standardized testing methods recommended by the American Thoracic Society were employed.
  • Data collected from a large sample of Korean children.

Main Results:

  • PEFR demonstrated a positive correlation with height, age, weight, sitting height, and body surface area (BSA).
  • Height and BSA were identified as the strongest predictors of PEFR.
  • Established reference values for PEFR in Korean children were higher than previously reported values in Korea.

Conclusions:

  • Successfully established reference values for PEFR using the MWPFM in Korean children residing in Seoul.
  • The developed percentile curves for PEFR as a function of height will support clinical decision-making for pediatric asthma management in Korea.
Abstract

Related Concept Videos

Respiratory Volumes and Capacities01:22

Respiratory Volumes and Capacities

The respiratory system is responsible for the intake of oxygen and the expulsion of carbon dioxide from the body. Respiratory volumes describe the volume of air in the lungs at different phases of the respiratory cycle. Tidal volume is the air breathed in and out during normal, quiet breathing. Inspiratory reserve volume is the air that can be forcefully inspired beyond the tidal volume. In contrast, expiratory reserve volume refers to the air that can be expelled from the lungs after a normal...
Respiratory Volumes01:15

Respiratory Volumes

Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...