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Published on: January 29, 2018
Nutrition and bone growth in pediatrics
Galia Gat-Yablonski1, Michal Yackobovitch-Gavan, Moshe Phillip
1The Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, 14 Kaplan Street, Petah Tikva 49202, Israel.
Pediatric Clinics of North America
|October 11, 2011
Summary
Adequate nutrition is essential for children's linear growth, involving building blocks and regulatory factors. This study explores growth plate development, hormonal influences, and new nutritional regulators impacting child development.
Area of Science:
- Pediatric Endocrinology
- Nutritional Science
- Developmental Biology
Background:
- Children's linear growth is a key indicator of normal development.
- Nutrition significantly impacts childhood growth, providing building materials and regulatory signals.
- The growth plate is a critical site for longitudinal bone growth.
Purpose of the Study:
- To describe the growth processes within the growth plate.
- To discuss the role of nutrition-affected hormones in growth.
- To explore local regulators and nutritional factors influencing growth, identifying potential new regulatory factors.
Main Methods:
- Review of existing literature on growth plate biology.
- Analysis of hormonal and local regulatory mechanisms in child growth.
- Discussion of nutritional impacts on growth plate function.
Main Results:
- Growth plate development is influenced by both systemic hormones and local factors.
- Nutrition plays a dual role, supplying structural components and modulating regulatory pathways.
- Emerging evidence suggests novel regulatory factors are involved in nutrient-to-growth translation.
Conclusions:
- Understanding growth plate dynamics is crucial for addressing childhood growth issues.
- Hormonal and local nutritional factors intricately regulate linear growth.
- Further research into new regulatory pathways could optimize nutritional interventions for child development.
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