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Related Concept Videos

Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Muscles of the Vertebral Column01:27

Muscles of the Vertebral Column

The back muscles that lie deep into the thoracolumbar fascia are called intrinsic or true back muscles. These muscles are divided into four layers: superficial, intermediate, deep, and deepest layers.
Superficial Layer:
The superficial layer consists primarily of the splenius muscles, which include the splenius capitis and splenius cervicis. These muscles are mainly responsible for the head and cervical spine movements, including extension, rotation, and lateral bending. The splenius capitis...
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...

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Related Experiment Video

Updated: May 28, 2026

Biomechanical Changes Related to Low Back Pain: An Innovative Tool for Movement Pattern Assessment and Treatment Evaluation in Rehabilitation
06:28

Biomechanical Changes Related to Low Back Pain: An Innovative Tool for Movement Pattern Assessment and Treatment Evaluation in Rehabilitation

Published on: December 13, 2024

Non-specific low back pain.

Federico Balagué1, Anne F Mannion, Ferran Pellisé

  • 1Department of Rheumatology, Physical Medicine, and Rehabilitation, Hôpital Fribourgeois-Hôpital cantonal, Fribourg and Geneva University, Geneva, Switzerland. balaguef@h-fr.ch

Lancet (London, England)
|October 11, 2011
PubMed
Summary

Non-specific low back pain is a global health issue affecting many adults. Management should prioritize self-care and evidence-based approaches, avoiding unnecessary surgery or overtreatment.

Related Experiment Videos

Last Updated: May 28, 2026

Biomechanical Changes Related to Low Back Pain: An Innovative Tool for Movement Pattern Assessment and Treatment Evaluation in Rehabilitation
06:28

Biomechanical Changes Related to Low Back Pain: An Innovative Tool for Movement Pattern Assessment and Treatment Evaluation in Rehabilitation

Published on: December 13, 2024

Area of Science:

  • Public Health
  • Epidemiology
  • Musculoskeletal Disorders

Background:

  • Non-specific low back pain (NLBP) is a significant global public health concern.
  • Lifetime prevalence reaches 84%, with chronic cases affecting 23% and causing disability in 11-12% of the population.
  • While mechanical factors are less critical, genetic predisposition plays a role in NLBP.

Purpose of the Study:

  • To provide an overview of non-specific low back pain.
  • To discuss diagnostic and management strategies for low back pain.
  • To emphasize evidence-based and patient-centered care.

Main Methods:

  • Review of diagnostic guidelines emphasizing history taking and clinical examination.
  • Recommendation to restrict the use of clinical imaging in diagnosis.
  • Consideration of patient preferences alongside clinical evidence for treatment.

Main Results:

  • The pathogenic role of mechanical factors is likely minor; genetic factors are important.
  • Effect sizes for many treatments are low, and their mechanisms of action are often unclear.
  • Self-management with support is generally recommended over surgery or overtreatment.

Conclusions:

  • Non-specific low back pain requires a shift towards conservative, evidence-based management.
  • Restricting routine imaging and avoiding overtreatment are crucial.
  • Empowering patients through self-management is key to addressing this widespread health problem.