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Updated: May 28, 2026
08:31
A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Patient selection for MitraClip therapy impaired left ventricular systolic function
F Maisano1, C Godino, A Giacomini
1Department of Cardiosurgery, San Raffaele Hospital, Milan, Italy. francesco.maisano@hsr.it
Minerva Cardioangiologica
|October 11, 2011
Summary
The MitraClip procedure offers a less invasive option for mitral regurgitation (MR). Patient selection is key, with the device showing promise for specific degenerative and functional MR cases, especially in high-surgical-risk patients.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Devices
Background:
- Mitral regurgitation (MR) is a significant condition with poor outcomes if untreated.
- Transcatheter interventions are emerging as less invasive alternatives to surgery.
- The MitraClip is currently the sole catheter-based procedure for MR in clinical practice.
Purpose of the Study:
- To review the clinical potential of the MitraClip procedure.
- To focus on patient selection criteria for this novel therapy.
- To clarify decision-making in degenerative MR (DMR) versus functional MR (FMR).
Main Methods:
- Review of preclinical studies, registries, and FDA-approved clinical trials (EVEREST, ACCESS-EU).
- Analysis of anatomical and clinical factors influencing patient selection.
- Evaluation of MitraClip's efficacy in different MR types and patient risk profiles.
Main Results:
- MitraClip is effective for specific types of functional MR (Type II or IIIb) and degenerative MR.
- Patient selection based on anatomical criteria (e.g., EVEREST criteria) predicts success, particularly in high-surgical-risk patients.
- MitraClip can be complementary to surgery or a primary option for high-risk FMR patients refractory to medical therapy.
Conclusions:
- MitraClip is a valuable tool for selected MR patients, especially those at high surgical risk.
- Careful patient selection based on anatomy and clinical factors is crucial for optimal outcomes.
- Future advancements in devices and imaging may broaden MitraClip's applicability and improve long-term durability.
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