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Relation between serum magnesium level and migraine attacks
Mahnaz Talebi1, Dariush Savadi-Oskouei, Mehdi Farhoudi
1Department of Neurology, Tabriz University of Medical Sciences, Tabriz, Iran.
Neurosciences (Riyadh, Saudi Arabia)
|October 11, 2011
Summary
Migraine patients have significantly lower serum magnesium levels than healthy individuals. Lower magnesium is linked to more frequent migraine attacks, suggesting magnesium supplementation may help treat and prevent migraines.
Area of Science:
- Neurology
- Biochemistry
Background:
- Migraine is a common neurological disorder.
- Serum magnesium levels have been investigated as a potential factor in migraine pathophysiology.
Purpose of the Study:
- To determine serum magnesium levels in migraine patients.
- To compare these levels with a healthy control group.
- To investigate the relationship between serum magnesium and migraine frequency.
Main Methods:
- A case-control study was conducted with 140 migraine patients and 140 healthy controls.
- Serum magnesium levels were measured in both groups.
- Data were analyzed to compare magnesium levels and assess correlations.
Main Results:
- Migraine patients exhibited significantly lower serum magnesium levels compared to controls (p=0.000).
- No significant difference in magnesium levels was found between migraine with aura and without aura subtypes.
- A significant linear relationship was observed between lower serum magnesium and increased headache frequency.
Conclusions:
- Serum magnesium is significantly lower in individuals with migraine.
- Magnesium levels correlate with the frequency of migraine attacks.
- These findings support the potential use of magnesium for migraine prevention and treatment.
