Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
Effects of EDTA on End-Point Detection Methods01:18

Effects of EDTA on End-Point Detection Methods

Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a result, EDTA...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Therapeutic vs. Recreational Use of Cocaine: Avoiding Diagnostic and Judicial Errors Through Interprofessional Collaboration-A Five-Case Report.

Healthcare (Basel, Switzerland)·2025
Same author

Difference in Central and Peripheral Total Tryptase Concentration/Level in Fatal Anaphylaxis: A Case Report.

The American journal of forensic medicine and pathology·2025
Same author

Preliminary Metabolomic Profiling of the Vitreous Humor from Hypothermia Fatalities.

Journal of proteome research·2021
Same author

Levels of haemolysis have no effect on femoral vein post-mortem tryptase levels.

Medicine, science, and the law·2021
Same author

Medicolegal Implications of Biphasic Anaphylaxis.

The American journal of forensic medicine and pathology·2020
Same author

Differences Between Central and Peripheral Postmortem Tryptase Levels.

The American journal of forensic medicine and pathology·2020

Related Experiment Video

Updated: May 28, 2026

Using a Chemical Biopsy for Graft Quality Assessment
05:00

Using a Chemical Biopsy for Graft Quality Assessment

Published on: June 17, 2020

Postmortem chemistry update part II.

Cristian Palmiere1, Patrice Mangin

  • 1University Centre of Legal Medicine, Lausanne-Geneva, Rue du Bugnon 21, 1011, Lausanne, Switzerland. cristian.palmiere@chuv.ch

International Journal of Legal Medicine
|October 11, 2011
PubMed
Summary
This summary is machine-generated.

This review covers new molecules for postmortem analysis in liver and cardiac conditions, alcohol misuse, inflammation, and sepsis. It highlights analytes like procalcitonin and C-reactive protein for forensic investigations.

More Related Videos

Pre-clinical Model of Cardiac Donation after Circulatory Death
06:26

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

Related Experiment Videos

Last Updated: May 28, 2026

Using a Chemical Biopsy for Graft Quality Assessment
05:00

Using a Chemical Biopsy for Graft Quality Assessment

Published on: June 17, 2020

Pre-clinical Model of Cardiac Donation after Circulatory Death
06:26

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

Area of Science:

  • Forensic chemistry and toxicology
  • Biomarker analysis in postmortem investigations

Background:

  • Builds upon "Postmortem Chemistry Update Part I."
  • Addresses advancements in forensic literature over the past two decades.
  • Focuses on molecules related to organ function, substance abuse, and critical conditions.

Purpose of the Study:

  • To review novel molecules relevant to postmortem diagnostics.
  • To discuss the application of these molecules in forensic casework.
  • To present findings from the authors' own observations where applicable.

Main Methods:

  • Comprehensive literature review of forensic science publications.
  • Analysis of molecules associated with liver and cardiac functions.
  • Investigation of biomarkers for alcohol misuse, myocardial ischemia, inflammation, sepsis, anaphylaxis, and hormonal disturbances.

Main Results:

  • Identified an array of new molecules of forensic interest.
  • Highlighted the current research status of biomarkers like procalcitonin and C-reactive protein for sepsis and inflammation.
  • Noted that many potential analytes are not yet routine in casework.

Conclusions:

  • Several novel molecules show promise for enhancing postmortem analysis.
  • Integration of advanced biomarkers into routine forensic practice requires further development.
  • Continued research is essential to leverage new biochemical findings in forensic investigations.