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Related Concept Videos

Biosynthesis of Polysaccharides01:26

Biosynthesis of Polysaccharides

Polysaccharides such as glycogen and starch are synthesized from nucleoside diphosphate sugars, primarily uridine diphosphate glucose (UDPG) and adenosine diphosphate glucose (ADPG). These activated glucose donors act as key intermediates in carbohydrate metabolism and biosynthesis. UDPG primarily involves glycogen synthesis in animals and many bacteria, while ADPG plays a fundamental role in starch synthesis in plants and certain bacteria.UDPG is formed when glucose-1-phosphate reacts with...
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
Chemistry of Carbohydrates03:25

Chemistry of Carbohydrates

Carbohydrates are an essential part of the diet in humans and animals. Grains, fruits, and vegetables are natural sources of carbohydrates that provide energy to the body, particularly through glucose, a simple sugar that is a component of starch and an ingredient in many staple foods. The stoichiometric formula (CH2O)n, where n is the number of carbons in the molecule represents carbohydrates. In other words, the ratio of carbon to hydrogen to oxygen is 1:2:1 in carbohydrate molecules. This...
Chemistry of the Cell02:58

Chemistry of the Cell

The cell is chemically composed of water, organic molecules and inorganic ions.
Water
The polarity of the water molecule and its resulting hydrogen bonding makes water a unique substance with special properties that are intimately tied to the processes of life. Life originally evolved in an aqueous environment, and most of an organism’s cellular chemistry and metabolism occur inside the aqueous contents of the cell’s cytoplasm. Special properties of water are its high heat capacity and heat of...
Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
Proteoglycans01:05

Proteoglycans

Glycans, a class of complex heterogeneous molecules, can be covalently attached to proteins to form glycosylated proteins that regulate various physiological and pathological processes. Glycosylated proteins or glycoproteins comprise N-linked and O-linked oligosaccharides. O-glycosylation is the most common type of protein glycosylation. Here, glycans attach to the oxygen atom of the hydroxyl groups of Serine or Threonine residues. O-linked glycosylation occurs later in protein processing,...

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Related Experiment Video

Updated: May 28, 2026

Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR
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Published on: February 12, 2019

Biophysical functionality in polysaccharides: from Lego-blocks to nano-particles.

Attilio Cesàro1, Barbara Bellich, Massimiliano Borgogna

  • 1Laboratory of Physical and Macromolecular Chemistry, Department of Life Sciences, University of Trieste, Via L. Giorgieri, 1, 34127 Trieste, Italy. cesaro@units.it

European Biophysics Journal : EBJ
|October 11, 2011
PubMed
Summary

This study explores biophysical concepts of polysaccharides, linking theoretical and experimental findings to industrial applications. Understanding polysaccharide properties is key for developing advanced materials like nanoparticles.

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Last Updated: May 28, 2026

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09:37

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Published on: February 12, 2019

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
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Area of Science:

  • Biophysics
  • Polymer Science
  • Materials Science

Background:

  • Polysaccharides are crucial biopolymers with diverse industrial applications.
  • Understanding their fundamental biophysical properties is essential for material development.

Purpose of the Study:

  • To elucidate key biophysical concepts related to polysaccharides.
  • To connect theoretical and experimental findings with industrial applications of polysaccharide-based materials.

Main Methods:

  • Utilizing simulation techniques and computational studies to interpret physicochemical properties.
  • Analyzing experimental data and employing statistical-thermodynamic models.

Main Results:

  • Interpreted physicochemical properties of polysaccharide aqueous solutions.
  • Discussed the role of ionic contributions in conformational transitions, aggregation, and phase separation.
  • Highlighted the importance of integrating experimental and theoretical data.

Conclusions:

  • Combined experimental and computational approaches are vital for understanding polysaccharide behavior.
  • Polysaccharide properties are critical for applications such as nanoparticle production.