Related Experiment Video
Updated: May 28, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
[Acute mesenteric ischemia]
1Klinik für Allgemein-, Gefäss- und Thoraxchirurgie, Chirurgische Klinik I, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Deutschland. joerg-peter.ritz@charite.de
Abstract:
Acute mesenteric ischemia (AMI) is a rare cause of acute abdomen. Coupled with a high patient age, non-specific clinical symptoms and a significant co-morbidity the disease is still associated with a significant mortality of 60-85%. With a combination of preexisting cardiac arrhythmia and sudden abdominal pain AMI should always first be ruled out. Contrast-enhanced computed tomography (CT) scanning has replaced angiography as the first diagnostic step, largely because both intravascular and intra-abdominal pathologies can be diagnosed. In the case of an acute abdomen or lack of immediate access to diagnostic tools, rapid surgical exploration should be preferred. Surgical therapy includes embolectomy and resection of ischemic bowel segments. There should be a wide indication for second-look surgery. The most important prognostic factor and the only factor that can be influenced by the surgeon is the time interval between onset of symptoms and surgery. Therefore angiography or laparotomy should be performed as early as possible in cases of suspected AMI.
Insights
Acute mesenteric ischemia (AMI), a rare cause of acute abdomen, has high mortality. Early diagnosis and surgical intervention are crucial for improving patient outcomes in this critical condition.
Area of Science:
- Gastroenterology
- Vascular Surgery
- Emergency Medicine
Context:
- Acute mesenteric ischemia (AMI) presents as a rare but critical cause of acute abdomen.
- High patient age, non-specific symptoms, and comorbidities contribute to a significant mortality rate (60-85%).
- Cardiac arrhythmia combined with sudden abdominal pain warrants immediate exclusion of AMI.
Purpose:
- To highlight the diagnostic and therapeutic challenges of acute mesenteric ischemia.
- To emphasize the importance of early diagnosis and surgical intervention.
- To review current diagnostic modalities and treatment strategies for AMI.
Summary:
- Contrast-enhanced computed tomography (CT) is the preferred initial diagnostic tool, identifying both intravascular and intra-abdominal pathologies.
- Rapid surgical exploration is recommended for acute abdomen or when diagnostic tools are unavailable.
- Surgical options include embolectomy, bowel resection, and a liberal approach to second-look surgery.
Impact:
- Prompt surgical intervention is the most significant modifiable prognostic factor.
- Reducing the time from symptom onset to surgery is critical for improving survival rates.
- Early angiography or laparotomy in suspected AMI cases can significantly improve patient outcomes.
More Related Videos
07:05Visualization of Neutrophil Extracellular Traps in Mesenteric Venules After Mesenteric Ischemia-Reperfusion Injury via Intravital Microscopy
Published on: September 27, 2024
04:57Controlled Reversible Visceral Arterial Ischemia, Venous Congestion and Combined Malperfusion via Midline Laparotomy in Rats
Published on: July 5, 2024
Related Concept Videos
Acute Coronary Syndrome I: Introduction
Acute Pancreatitis I: Introduction
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute Pancreatitis II: Clinical Manifestations and Management
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Transient Ischemic Attack l: Introduction