Related Experiment Video
Updated: May 28, 2026

Generating the Transcriptional Regulation View of Transcriptomic Features for Prediction Task and Dark Biomarker Detection on Small Datasets
Published on: March 1, 2024
Impact of disease on interferences in blood bioanalysis
1Stichting KCL, Department for Clinical Chemistry & Laboratory Medicine, Borniastraat 34, Leeuwarden, The Netherlands. a.wolthuis@kcl.znb.nl
Abstract:
Most diseases will influence the blood biochemical homeostasis. Analysis of these biochemical modifications is used for diagnostic purposes and for follow-up of treated patients. Sometimes, however, these disease-induced blood matrix modifications interfere with bioanalytical assays. As a consequence erroneous high or low results can be reported. This article focuses on these particular problems by using examples from the literature and discussions about possible mechanisms that may explain the interferences.
More Related Videos
11:28Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques
Published on: March 13, 2015
07:40Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis
Published on: March 20, 2021
Related Concept Videos
Effect of Hepatic Disease on Pharmacokinetics: Drug Dosing and Hepatic Blood Flow
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
Bioavailability: Influencing Factors
Factors Affecting Protein-Drug Binding: Drug Interactions
Displacement interactions can have varying outcomes, ranging from toxicity to virtually...
Effect of Hepatic Disease on Pharmacokinetics: Active Drug, Metabolite and Fraction of Metabolized Drug
Factors Influencing Drug Absorption: Disease States and Pharmacology
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...