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[Brain tumors: classification and clinical aspects].

P A Battistella1, R Ruffilli, F Viero

  • 1Dipartimento di Pediatria, Università di Padova, Italia.

La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics
|January 1, 1990
PubMed
Summary
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Pediatric brain tumors are common, often gliomas, with infratentorial locations prevalent. This review covers diagnosis and management of childhood brain tumors.

Area of Science:

  • Pediatric oncology
  • Neuro-oncology
  • Clinical neurology

Context:

  • Brain tumors are a significant cause of solid tumors in children, accounting for 40-50% of cases.
  • Gliomas constitute the majority (60-70%) of pediatric brain tumors.
  • The infratentorial compartment is the most common tumor location (60%), with cerebellar astrocytomas, medulloblastomas, and brain stem gliomas being equally prevalent.

Purpose:

  • To review the clinical symptoms associated with various pediatric brain tumors.
  • To outline instrumental diagnostic procedures for brain tumors in children.
  • To provide evidence-based management recommendations for childhood brain tumors.

Summary:

  • This review focuses on pediatric brain tumors, a major concern in childhood oncology.

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  • It details the incidence, common types (gliomas), and anatomical distribution (infratentorial predominance) of these tumors.
  • The analysis includes diagnostic methods and management strategies derived from clinical trials.

    • Impact:

    • Enhances understanding of pediatric brain tumor epidemiology and characteristics.
    • Provides a comprehensive overview of diagnostic approaches for clinicians.
    • Offers evidence-based guidelines for optimizing the management of childhood brain tumors.