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Related Concept Videos

Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
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Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

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Related Experiment Videos

Diverticulitis complicated by pylephlebitis: a case report.

Mahesh Gajendran1, Thiruvengadam Muniraj, Mohamed Yassin

  • 1University of Pittsburgh Medical Centre, Department of Medicine, 200 Lothrop Street, Pittsburgh, PA 15213, USA. gajendranm@upmc.edu.

Journal of Medical Case Reports
|October 12, 2011
PubMed
Summary
This summary is machine-generated.

Pylephlebitis, or septic thrombophlebitis of the portal venous system, can complicate common abdominal issues like diverticulitis. Prompt recognition and appropriate treatment of the infected portal vein thrombus are crucial for patient outcomes.

Related Experiment Videos

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Vascular Surgery

Background:

  • Pylephlebitis is septic thrombophlebitis of the portal venous system, often stemming from abdominal infections or inflammation.
  • Diverticulitis is a common condition that can lead to serious complications such as pylephlebitis.

Purpose of the Study:

  • To present a case of pylephlebitis secondary to sigmoid diverticulitis.
  • To highlight the importance of recognizing and appropriately treating infected portal vein thrombus.

Main Methods:

  • A 62-year-old female with a history of sigmoid diverticulitis presented with symptoms of abdominal pain, fever, and fatigue.
  • Diagnostic imaging revealed portal vein thrombosis and a sigmoid diverticulitis with an abscess.
  • Treatment included antibiotics (piperacillin-tazobactam, ertapenem), sigmoid colectomy, colostomy, and anticoagulation (enoxaparin).

Main Results:

  • The patient developed pylephlebitis secondary to sigmoid diverticulitis with an abscess.
  • Initial treatment led to clinical improvement and resolution of leukocytosis.
  • A subsequent pelvic abscess required drainage, while portal vein thrombus persisted and was managed with continued enoxaparin.

Conclusions:

  • This case underscores the significance of identifying infected portal vein thrombus in the context of diverticulitis.
  • Appropriate management, including antibiotics and anticoagulation, is essential for addressing pylephlebitis.